The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation - structural insights into pneumococcal biofilm formation

    T. Schulte, C. Mikaelsson, A. Beaussart, A. Kikhney, M. Deshmukh, S. Wolniak, A. Pathak, C. Ebel, J. Löfling, B. Henriques-Normark, Y. F. Dufrêne, D. Svergun, P. Nygren, A. Achour

Scientific reports

2016,  6:32371

Sticky Matrix: Adhesion Mechanisms of the Staphylococcal Polysaccharide Intercellular Adhesin
C. Formosa-Dague,C. Feuillie, A. Beaussart, S. Derclaye, S. Kucharikova, I. Lasa, P. VanDijck, Y.F. Dufrêne

ACS Nano 

2016, 10, 3443

Effect of LRP-1 Silencing on the Invasive Potential of Cancer Cells by Nanomechanical Probing and Adhesion Force Measurements using Atomic Force Microscopy

A. Le Cigne, L. Chieze, A. Beaussart, S. El-Kirat-Chatel, Y.F. Dufrêne, S. Dedieu, C. Schneider, L. Martiny, J. Devy, M. Molinari.


2016, 8, 7144

Force nanoscopy as a versatile Platform for Anti-adhesion Therapy targeting Bacterial Pathogens

A. Beaussart, M. Abellán-Flos, S. El-Kirat-Chatel, S. P. Vincent, Y. F. Dufrêne

Nano  Letters

2016, 16, 1299

The Human Disease-Associated Aβ Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin

R.D. Rameau, D.N. Jackson, A. Beaussart, Y. F. Dufrêne, P.N. Lipke


2016, 7:1, e01815-15


Blastomyces virulence adhesin-1 protein binding to glycosaminoglycans is enhanced by protein disulfide isomerase

A. Beaussart, T. Brandhorst, Y.F. Dufrêne, B.S. Klein


2015, 6:5, e01403-15

Nanoscale biophysical properties of the cell surface galactosaminogalactan from the fungal pathogen Aspergillus fumigatus

A. Beaussart, S. El-Kirat, T. Fontaine, J.-P. Latgé, Y.F. Dufrêne


2015,  7, 14996

Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata

*S. El-Kirat-Chatel, *A. Beaussart, S. Derclaye, D. Alsteens, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne

ACS Nano

2015, 9, 1648

 Identification of a Supramolecular Functional Architecture of Streptococcus mutans Adhesin P1 on the Bacterial Cell Surface

K. Heim, R.M.A. Sullan, P. Crowley, S. El-Kirat-Chatel, A. Beaussart, W. Tang, R. Besingi, Y.F. Dufrêne, J. Bready

J. Biol. Chem.,

2015, 290, 9002

Forces in yeast flocculation

S. El-Kirat-Chatel, A. Beaussart, S.P. Vincent, M. Abellan Flos, P. Hols, P.N. Lipke, Y.F. Dufrêne


2015,  7, 1760


Cell cycle constraints on capsulation and genetic exchange

S. Ardisson, C. Fumeaux, M. Bergé, A. Beaussart, L. Théraulaz, S.K. Kadhakrishnan, Y.F. Dufrêne, P.H. Viollier


2014, 3,e03587

In situ particle film ATR FTIR spectroscopy of poly (N-isopropyl acrylamide) (PNIPAM) adsorption onto talc

D. A. Beattie, J. Addai-Mensah, A. Beaussart, G. V. Franks, K. Y. Yeap

Phys. Chem. Chem. Phys.

2015, 16, 25143

Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae

A. Beaussart, C. Péchoux, P. Trieu, M.Y. Mistou, Y. Dufrêne


2014, 6, 14820

Nanoscale adhesion forces of Pseudomonas aeruginosa type IV pili

A. Beaussart, A.E. Baker, S.L. Kuchma, S. El-Kirat-Chatel, G.A. O'Toole, Y.F. Dufrêne

ACS Nano

2014, 8, 10723

The binding force of the staphylococcal adhesin SdrG is remarkably strong

P. Herman, S. El-Kirat-Chatel, A. Beaussart, T. Foster, Y.F. Dufrêne

Mol. Mic.

2014, 93, 356

Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response

J. Bayry, A. Beaussart, Y.F. Dufrêne , M. Sharma, K. Bansal, O. Kniemeyer, V. Aimanianda, A. A. Brakhage, S. V. Kaveri, K. J. Kwon-Chung, J-P Latgé, A. Beauvais

Infect.  Immun.

2014, 82, 3141

Quantifying the forces guiding microbial cell adhesion using single-cell force spectroscopy

A. Beaussart, S. El-Kirat-Chatel, R. M. A. Sullan,D. Alsteens, P. Herman, S. Derclaye, Y.F. Dufrêne

Nat. Protoc.

2014, 9, 1049

Atomic force microscopy and spectroscopy: a versatile toolbox to decipher Candida albicans pathogenicity

A. Beaussart and S. El-Kirat-Chatel

J. Bionanoscience

2014, 8, 419

Single-cell force spectroscopy of pili-mediated adhesion

*R. M. A. Sullan, *A. Beaussart, P. Tripathi, S. Derclaye, S. El-Kirat-Chatel, J.K. Li, Y.J. Schneider, J. Vanderleyden, S. Lebeer, Y.F. Dufrêne


2014, 6, 1134

Single-cell and single-molecule analysis deciphers the localization, adhesion and mechanics of the biofilm adhesin LapA

S. El-Kirat-Chatel, A. Beaussart, C. D. Boyd, G. A. O'Toole, Y.F. Dufrêne

ACS  Chem. Biol.

2014, 9, 485

Chemical force microscopy of stimuli-responsive adhesive copolymers

A. Beaussart, T.C. Ngo, S. Derclaye, R. Kalinova, R. Mincheva, P. Dubois, R. Lazzaroni, P. Leclère , Y.F. Dufrêne


2014, 6, 565


Forces driving the attachment of Staphyloccocus epidermidis to fibrinogen-coated surfaces

P. Herman, S. El-Kirat-Chatel, A. Beaussart, J. Geoghegan, T. Vanzieleghem, T. Foster, P. Hols, J. Mahillon, Y.F. Dufrêne


2013, 29, 13018

Single-cell force spectroscopy of the medically-important Staphyloccocus epidermidis-Candida albicans interaction
A. Beaussart, P. Herman, S. El-Kirat-Chatel, P.N. Lipke, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne


2013, 5, 10894

Single-molecule atomic force microscopy unravels the binding mechanism of a Burkholderia cenocepacia trimeric autotransporter adhesin.

S. El-Kirat-Chatel, D. Mil-Homens, A. Beaussart, A.M Fialho, Y.F. Dufrêne

Mol. Mic.

2013, 89, 649

Single-cell force spectroscopy of Als mediated fungal adhesion

D. Alsteens, A. Beaussart, S. Derclaye, S. El-Kirat-Chatel, H.R. Park, P.N. Lipke, Y.F. Dufrêne

Anal. Methods

2013, 20, 3657

Binding mechanism of the bacterial autolysin Acm2: low affinity, broad specificity and multifunctionality

A. Beaussart, T. Rolain, M. C. Duchêne, G. Andre, P. Hols, Y.F. Dufrêne

Biophys. J.

2013, 105, 620

O-glycosylation as a novel control mechanism of peptidoglycan hydrolase activity

T. Rolain, E. Bernard, A. Beaussart, H. Degand, P. Courtin, W. Egge-Jacobsen, P. A. Bron, P. Morsomme, M. Kleerebezem, M-P Chapot-Chartier, Y. F. Dufrêne, P. Hols

J.  Biol. Chem.

2013, 288, 22233

Atomic force microscopy: a new look at pathogens

D. Alsteens, A. Beaussart, S. El-Kirat-Chatel, R. Sullan, Y.F. Dufrêne

PloS  Pathog.

2013, 9:9

Single-molecule analysis of the major glycopolymers of pathogenic and non-pathogenic yeast cells

S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, A. Sarazin, T. Jouault, Y.F. Dufrêne


2013, 5, 4855

Single-cell force spectroscopy of probiotic bacteria

A. Beaussart, S. El-Kirat-Chatel, P. Herman, D. Alsteens, J. Mahillon, P. Hols, Y.F. Dufrêne

Biophys. J.

2013, 104, 1886

Adhesion and nanomechanics of pili from probiotic Lactobacillus rhamnosus GG

*P. Tripathi, *A. Beaussart, D. Alsteens, V. Dupres, I. Claes, I von Ossowski, A. Palva, S. Lebeer, J. Vanderleyden, Y.F. Dufrêne

ACS Nano

2013, 7, 3685


Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans

S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, D.N Jackson, P.N. Lipke PN, Y.F. Dufrêne


2012, 5, 1105

Single-molecule imaging and functional analysis of Als adhesins and mannans during Candida albicans morphogenesis

A. Beaussart, D. Alsteens, S. El-Kirat-Chatel, P.N. Lipke, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne

ACS Nano

2012, 6, 10950

Towards a nanoscale view of lactic acid bacteria

P. Tripathi, A. Beaussart, G. Andre, T. Rolain, S. Lebeer, J. Vanderleyden, P. Hols, Y.F. Dufrêne


2012, 43, 1323

Looking at mechanosensors on the cell surface

J.J. Heinisch, P.N. Lipke, A. Beaussart, S. El-Kirat-Chatel, V. Dupres, D. Alsteens, Y.F. Dufrêne

J. Cell Science

2012, 125, 4189

In situ ATR FTIR study of dextrin adsorption on anatase TiO2

A. Beaussart, L. Petrone, A. Mierczynska-Vasilev, A.J. McQuillan, D.A. Beattie


2012, 28, 4233

Adsorption of modified dextrins on molybdenite: AFM imaging, contact angle, and flotation studies

A. Beaussart, L. Parkinson, A. Mierczynska-Vasilev, D.A. Beattie

J. Colloid Inter.  Sci.

2012, 368, 608

Deciphering the nanometer-scale organization and assembly of Lactobacillus rhamnosus GG pili using atomic force microscopy

P. Tripathi, V. Dupres, A. Beaussart, S. Lebeer, I.J.J Claes, J. Vanderleyden, Y.F. Dufrêne


2012, 28, 2211

Synchrotron FTIR microscopy of Langmuir-Blodgett monolayers and polyelectrolyte multilayers at the solid-solid interface

D.A. Beattie, A. Beaussart, A. Mierczynska-Vasilev, S.L. Harmer, B. Thierry, L. Puskar, M. Tobin 


2012, 28, 1683


The role of mineral surface chemistry in modified dextrin adsorption

A. Beaussart, A. Mierczynska-Vasilev, S.L. Harmer, D.A. Beattie

J. Colloid Inter. Sci.

2011, 357, 510


Evolution of carboxymethyl cellulose layer morphology on hydrophobic mineral surfaces: variation of polymer concentration and ionic strength

A. Beaussart, A. Mierczynska-Vasilev, D. A. Beattie

J. Colloid Inter. Sci.

2010, 346, 303


Effect of adsorbed polymers on bubble particle attachment

A. Beaussart, L. Parkinson, A. Mierczynska-Vasilev, J. Ralston, D. A. Beattie


2009, 25, 13290

Adsorption of dextrin on hydrophobic minerals

A. Beaussart, A. Mierczynska-Vasilev, D. A. Beattie


2009, 25, 9913


Transfer of apatite coating from porogens to scaffolds: uniform apatite coating within porous (DL-lactic-co-glycolic acid) scaffold in vitro

J. Li, A. Beaussart, Y. Chen, A.F.T. Mak

J. Biomed.  Mater. Res.

2007, 80, 226